Rawson, Timothy M 
ORCID: 0000-0002-2630-9722, Wilson, Richard C ORCID: 0000-0002-3275-6932, Moore, Luke SP, Macgowan, Alasdair P, Lovering, Andrew M, Bayliss, Mark, Kyriakides, Mathew, Gilchrist, Mark, Roberts, Jason A, Hope, William W ORCID: 0000-0001-6187-878X et al (show 1 more authors)
(2021)
Exploring the Pharmacokinetics of Phenoxymethylpenicillin (Penicillin-V) in Adults: A Healthy Volunteer Study.
OPEN FORUM INFECTIOUS DISEASES, 8 (12).
ofab573-.
Abstract
This healthy volunteer study aimed to explore phenoxymethylpenicillin (penicillin-V) pharmacokinetics (PK) to support the planning of large dosing studies in adults. Volunteers were dosed with penicillin-V at steady state. Total and unbound penicillin-V serum concentrations were determined, and a base population PK model was fitted to the data.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | healthy volunteers, oral dosing, penicillin-V, pharmacokinetics, population PK modeling |
| Divisions: | Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Systems, Molecular and Integrative Biology |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 27 May 2022 08:33 |
| Last Modified: | 18 Jan 2023 21:00 |
| DOI: | 10.1093/ofid/ofab573 |
| Open Access URL: | https://doi.org/10.1093/ofid/ofab573 |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3155589 |
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