The Birmingham and Black Country cohort of Venous Thromboembolism (BBC-VTE) registry: Rationale, design and preliminary results.



Sanders, Alexander, El-Bouri, Wahbi K ORCID: 0000-0002-2732-5927, Lip, Gregory YH and *BBC-VTE investigators,
(2022) The Birmingham and Black Country cohort of Venous Thromboembolism (BBC-VTE) registry: Rationale, design and preliminary results. European journal of internal medicine, 97. pp. 50-55.

[img] Text
Revision Main text file EJIM - wkeb edits39581 - 131221.pdf - Author Accepted Manuscript

Download (321kB) | Preview

Abstract

The Birmingham Black Country Venous Thromboembolism registry (BBC-VTE) is a multi-ethnic cohort of patients who suffered a first episode of venous thromboembolism (VTE) and were admitted to various hospital sites across the West Midlands and Black Country regions in the United Kingdom. The BBC-VTE registry is a retrospective, observational cohort study which aims to collect data on outcomes including mortality, bleeding and VTE recurrence in this patient cohort. In addition, the comprehensive, structured data collected will allow us to conduct machine learning analyses for risk prediction in such patients and also to compare to previously derived mortality scores such as the PESI and the simplified PESI (sPESI). Our registry included 2183 patients admitted to hospital between the years 2012-14 and 2016-18 with a first episode of VTE and the mean follow up was 36 months. The cohort was ethnically diverse with 72.5% white Caucasian, 8.2% Asian (including South Asian), 6.7% black, and 11.7% of unknown/other ethnicity. Of those admitted during the collection period 56% had PE, 40% had DVT, with the rest presenting with both PE and DVT. Around 7% of patients went on to develop a bleeding episode and 36% died (all-cause mortality). Of the deaths, 10% of patients died within 30-days of admission (30-day mortality), with 16% dying within 90 days. In summary, this study investigates real-world outcomes of patients after the first index VTE event and attempts to bridge the gap in evidence for contemporary data in this population which will allow to construct more accurate risk prediction tools and management decisions.

Item Type: Article
Uncontrolled Keywords: *BBC-VTE investigators
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences
Depositing User: Symplectic Admin
Date Deposited: 09 Jun 2022 09:51
Last Modified: 22 Jan 2023 02:30
DOI: 10.1016/j.ejim.2022.01.022
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3156103