What will the cardiovascular disease slowdown cost? Modelling the impact of CVD trends on dementia, disability, and economic costs in England and Wales from 2020-2029.


Collins, Brendan ORCID: 0000-0002-3023-8189, Bandosz, Piotr ORCID: 0000-0002-6395-6216, Guzman-Castillo, Maria, Pearson-Stuttard, Jonathan, Stoye, George, McCauley, Jeremy, Ahmadi-Abhari, Sara ORCID: 0000-0003-4440-4050, Araghi, Marzieh, Shipley, Martin J, Capewell, Simon et al (show 3 more authors) (2022) What will the cardiovascular disease slowdown cost? Modelling the impact of CVD trends on dementia, disability, and economic costs in England and Wales from 2020-2029. PloS one, 17 (6). e0268766-.

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Abstract

<h4>Background</h4>There is uncertainty around the health impact and economic costs of the recent slowing of the historical decline in cardiovascular disease (CVD) incidence and the future impact on dementia and disability.<h4>Methods</h4>Previously validated IMPACT Better Ageing Markov model for England and Wales, integrating English Longitudinal Study of Ageing (ELSA) data for 17,906 ELSA participants followed from 1998 to 2012, linked to NHS Hospital Episode Statistics. Counterfactual design comparing two scenarios: Scenario 1. CVD Plateau-age-specific CVD incidence remains at 2011 levels, thus continuing recent trends. Scenario 2. CVD Fall-age-specific CVD incidence goes on declining, following longer-term trends. The main outcome measures were age-related healthcare costs, social care costs, opportunity costs of informal care, and quality adjusted life years (valued at £60,000 per QALY).<h4>Findings</h4>The total 10 year cumulative incremental net monetary cost associated with a persistent plateauing of CVD would be approximately £54 billion (95% uncertainty interval £14.3-£96.2 billion), made up of some £13 billion (£8.8-£16.7 billion) healthcare costs, £1.5 billion (-£0.9-£4.0 billion) social care costs, £8 billion (£3.4-£12.8 billion) informal care and £32 billion (£0.3-£67.6 billion) value of lost QALYs.<h4>Interpretation</h4>After previous, dramatic falls, CVD incidence has recently plateaued. That slowdown could substantially increase health and social care costs over the next ten years. Healthcare costs are likely to increase more than social care costs in absolute terms, but social care costs will increase more in relative terms. Given the links between COVID-19 and cardiovascular health, effective cardiovascular prevention policies need to be revitalised urgently.

Item Type: Article
Uncontrolled Keywords: Humans, Dementia, Cardiovascular Diseases, Longitudinal Studies, Quality-Adjusted Life Years, Cost-Benefit Analysis, Health Care Costs, England, Wales, COVID-19
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Population Health
Depositing User: Symplectic Admin
Date Deposited: 11 Jul 2022 15:38
Last Modified: 18 Jan 2023 20:56
DOI: 10.1371/journal.pone.0268766
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3158212
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