Dionyssiotis, Yannis 
ORCID: 0000-0001-6962-1583, Athanassiou, Panagiotis, Papathanasiou, Jannis ORCID: 0000-0003-2557-5508, Efstathopoulos, Efstathios, Prokopidis, Konstantinos ORCID: 0000-0002-6264-9388, Trovas, Georgios and Kostoglou-Athanassiou, Ifigenia
(2022)
Sarcopenia in patients with diabetes mellitus.
Folia medica, 64 (4).
pp. 596-601.
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Abstract
<h4>Introduction</h4>Diseases such as diabetes mellitus may be associated with adverse changes in body composition. Sarcopenia is characterized by a progressive and generalized loss of skeletal muscle mass and functionality.<h4>Aim</h4>To investigate the relationship between type 2 diabetes mellitus (T2DM) and sarcopenia.<h4>Materials and methods</h4>In a retrospective, non-randomized study, 35 T2DM patients, aged 20-80 years, were assessed for sarcopenia prevalence compared to controls (n=16). Appendicular skeletal mass (ASM) (kg) was measured, and sarcopenia was defined as SMI <7.0 and <5.7 kg/m2, in males and females, respectively, using the European Working Group on Sarcopenia in Elderly (EWGOSP) definition. Low physical performance was defined as a walking speed of <0.8 m/s.<h4>Results</h4>Incidence of sarcopenia was significantly higher in T2DM patients vs. controls (27% vs. 20%, p=0.01) and elderly vs. young participants (40% vs. 12%, p<0.001), respectively. Walking velocity was significantly lower in T2DM patients compared to male and female controls (1.08±0.22 vs. 1.23±0.18 and 1.07±0.26 vs. 1.26±0.16, respectively, p<0.001,).<h4>Conclusions</h4>A moderate prevalence of sarcopenia in patients with type 2 diabetes mellitus was observed, which appeared to increase significantly in older men. Finally, incidence of T2DM displayed decreased physical performance in both genders.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Muscle, Skeletal, Humans, Diabetes Mellitus, Type 2, Prevalence, Retrospective Studies, Body Composition, Aged, Female, Male, Sarcopenia |
| Divisions: | Faculty of Health and Life Sciences |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 09 Sep 2022 07:44 |
| Last Modified: | 18 Jan 2023 20:45 |
| DOI: | 10.3897/folmed.64.e63530 |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3163911 |
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