Association between exercise habit changes and mortality following a cardiovascular event



Kang, Dong-Seon, Sung, Jung-Hoon, Kim, Daehoon, Jin, Moo-Nyun, Jang, Eunsun, Yu, Hee Tae, Kim, Tae-Hoon, Pak, Hui-Nam, Lee, Moon-Hyoung, Lip, Gregory ORCID: 0000-0002-7566-1626
et al (show 2 more authors) (2022) Association between exercise habit changes and mortality following a cardiovascular event. HEART, 108 (24). pp. 1945-1951.

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Abstract

<h4>Objective</h4>To investigate the associations between exercise habit changes following an incident cardiovascular event and mortality in older adults.<h4>Methods</h4>We analysed the relationship between exercise habit change and all-cause, cardiovascular and non-cardiovascular deaths in adults aged ≥60 years between 2003 and 2012 who underwent two consecutive health examinations within 2 years before and after diagnosis of cardiovascular disease (CVD). They were categorised into four groups according to exercise habit changes: persistent non-exercisers, exercise dropouts, new exercisers and exercise maintainers. Differences in baseline characteristics were adjusted using inverse probability of treatment weighting.<h4>Results</h4>Of 6076 participants, the median age was 72 (IQR 69-76) years and men accounted for 50.6%. Compared with persistent non-exercisers (incidence rate (IR) 4.8 per 100 person-years), new exercisers (IR 3.5, HR 0.73, 95% CI 0.58 to 0.91) and exercise maintainers (IR 2.9, HR 0.53, 95% CI 0.38 to 0.73) were associated with reduced risk of all-cause death. The rate of non-cardiovascular death was significantly lower in new exercisers (IR 2.3, HR 0.73, 95% CI 0.56 to 0.95) and exercise maintainers (IR 2.3, HR 0.61, 95% CI 0.42 to 0.90) than in persistent non-exercisers (IR 3.2). Also, trends towards reduced cardiovascular death in new exercisers and exercise maintainers were observed (p value for trend <0.001).<h4>Conclusions</h4>More virtuous exercise trajectories in older adults with CVD are associated with lower mortality rates. Our results support public health recommendations for older adults with CVD to perform physical activity.

Item Type: Article
Uncontrolled Keywords: Humans, Cardiovascular Diseases, Exercise, Incidence, Mortality, Risk Factors, Habits, Aged, Male
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences
Depositing User: Symplectic Admin
Date Deposited: 25 Oct 2022 15:06
Last Modified: 25 Feb 2023 01:49
DOI: 10.1136/heartjnl-2022-320882
Open Access URL: https://heart.bmj.com/content/early/2022/05/18/hea...
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URI: https://livrepository.liverpool.ac.uk/id/eprint/3165753