Sex and gender differences in community-acquired pneumonia



Corica, Bernadette ORCID: 0000-0001-9460-4435, Tartaglia, Francesco, D'Amico, Tania, Romiti, Giulio Francesco and Cangemi, Roberto
(2022) Sex and gender differences in community-acquired pneumonia. INTERNAL AND EMERGENCY MEDICINE, 17 (6). pp. 1575-1588.

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Abstract

Awareness of the influence of sex ands gender on the natural history of several diseases is increasing. Community-acquired pneumonia (CAP) is the most common acute respiratory disease, and it is associated with both morbidity and mortality across all age groups. Although a role for sex- and gender-based differences in the development and associated complications of CAP has been postulated, there is currently high uncertainty on the actual contribution of these factors in the epidemiology and clinical course of CAP. More evidence has been produced on the topic during the last decades, and sex- and gender-based differences have also been extensively studied in COVID-19 patients since the beginning of the SARS-CoV-2 pandemic. This review aims to provide an extensive outlook of the role of sex and gender in the epidemiology, pathogenesis, treatment, and outcomes of patients with CAP, and on the future research scenarios, with also a specific focus on COVID-19.

Item Type: Article
Uncontrolled Keywords: Pneumonia, Sex, Gender, COVID-19, Review
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences
Depositing User: Symplectic Admin
Date Deposited: 31 Oct 2022 16:18
Last Modified: 18 Jan 2023 19:48
DOI: 10.1007/s11739-022-02999-7
Open Access URL: https://doi.org/10.1007/s11739-022-02999-7
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3165908