COVID-19 and Clinically Isolated Syndrome: Coincidence or Causative Link? A 12-Month Follow-Up Case Report

Romano, Davide, Macerollo, Antonella ORCID: 0000-0003-4322-2706, Giannaccare, Giuseppe, Mazzuca, Daniela, Borgia, Alfredo, Romano, Vito ORCID: 0000-0002-5148-7643, Semeraro, Francesco and Ellis, Richard (2022) COVID-19 and Clinically Isolated Syndrome: Coincidence or Causative Link? A 12-Month Follow-Up Case Report. APPLIED SCIENCES-BASEL, 12 (22). p. 11531.

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Official URL: http://dx.doi.org/10.3390/app122211531

Abstract

<jats:p>A 35-year-old female with positive anamnesis of COVID-19 infection presented with a seven-day history of headache along with tingling and numbness involving the right lower limb and visual disturbance on the right side of her vision. Magnetic resonance imaging (MRI) of the brain and C-spine were consistent with acute demyelinating lesions. However, the MAGNIMS criteria for a multiple sclerosis diagnosis were not met, and, subsequently, a diagnosis of clinically isolated syndrome (CIS) was made. At 12 months, the patient showed new inflammatory lesions in the right frontal lobe and at the septocallosal interface, a lesion of the right hemi-cord at C3, and subsequent development of vertigo and unsteadiness and signs consistent with a brainstem/cerebellar relapse. On the basis of clinical and radiological criteria in the 2017 McDonald criteria, a diagnosis of relapsing remitting multiple sclerosis was made.</jats:p>

Item Type:	Article
Uncontrolled Keywords:	a COVID-19 infection, neurological manifestations, ocular manifestations, causative link, legal medicine, CNS inflammatory
Divisions:	Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Clinical Directorate
Depositing User:	Symplectic Admin
Date Deposited:	15 Dec 2022 15:15
Last Modified:	15 Mar 2024 12:47
DOI:	10.3390/app122211531
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3166699