Wang, Ding Mei, Zhang, Yi, Jiang, Yuan, Ye, Ying, Huang, Xiang Yuan, Li, Meng Ru, Ji, Mi, Zhao, Zheng Shan, Chen, Xiao Tian, Sheng, Wei et al (show 5 more authors)
(2020)
Folic Acid Supplementation in Chinese Peri-conceptional Population: Results from the SPCC Study.
BIOMEDICAL AND ENVIRONMENTAL SCIENCES, 33 (8).
557-+.
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Abstract
<h4>Objective</h4>To determine the prevalence and determinants of folic acid (FA) supplementation in Chinese couples planning for pregnancy and in women during early pregnancy.<h4>Methods</h4>This was a cross-sectional study based on the Shanghai PreConception Cohort (SPCC) study. Data on FA supplementation and socio-demographic features were collected using questionnaires. Couples visiting clinics for pre-pregnancy examination and pregnant women at < 14 gestational weeks were recruited in Shanghai, China, between March 2016 and September 2018.<h4>Results</h4>Among the pregnancy planners, 42.4% (4,710/11,099) women and 17.1% (1,377/8,045) men used FA supplements, while 93.4% (14,585/15,615) of the pregnant women used FA supplements. FA supplement use was higher in female pregnancy planners who were older ( <i>RR</i>: 1.13, 95% <i>CI</i>: 1.08-1.18), had higher education ( <i>RR</i>: 1.71, 95% <i>CI</i>: 1.53-1.92), and were residing in urban districts ( <i>RR</i>: 1.06, 95% <i>CI</i>: 1.01-1.11) of FA supplementation; female pregnancy planners with alcohol consumption ( <i>RR</i>: 0.95, 95% <i>CI</i>: 0.90-0.99) had lower odds of FA supplementation. In early pregnancy, women with higher educational level ( <i>RR</i>: 1.04, 95% <i>CI</i>: 1.03-1.06), who underwent pre-pregnancy examination ( <i>RR</i>: 1.02, 95% <i>CI</i>: 1.01-1.03) had higher odds of using an FA supplement; older aged ( <i>RR</i>: 0.99, 95% <i>CI</i>: 0.98-0.99), and multigravida ( <i>RR</i>: 0.97, 95% <i>CI</i>: 0.96-0.98) had lower odds of FA supplementation.<h4>Conclusion</h4>Although the majority of pregnant women took FA supplements, more than half of the women planning for pregnancy did not. Urgent strategies are needed to improve pre-conception FA supplementation.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Folic acid supplementation, Peri-conception, Birth defects, China, Pregnancy |
| Divisions: | Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Faculty Management Office |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 23 Dec 2022 08:26 |
| Last Modified: | 23 Dec 2022 08:26 |
| DOI: | 10.3967/bes2020.074 |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3166763 |
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