On the application of 3d metals for C-H activation toward bioactive compounds: The key step for the synthesis of silver bullets

Carvalho, Renato L, Miranda, Amanda S de, Nunes, Mateus P, Gomes, Roberto S, Jardim, Guilherme AM and Junior, Eufranio N da Silva (2021) On the application of 3d metals for C-H activation toward bioactive compounds: The key step for the synthesis of silver bullets. BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 17 (1). pp. 1849-1938.

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Official URL: http://dx.doi.org/10.3762/bjoc.17.126

Abstract

Several valuable biologically active molecules can be obtained through C-H activation processes. However, the use of expensive and not readily accessible catalysts complicates the process of pharmacological application of these compounds. A plausible way to overcome this issue is developing and using cheaper, more accessible, and equally effective catalysts. First-row transition (3d) metals have shown to be important catalysts in this matter. This review summarizes the use of 3d metal catalysts in C-H activation processes to obtain potentially (or proved) biologically active compounds.

Item Type:	Article
Uncontrolled Keywords:	bioactive compounds, C-H activation, 3d metals, drugs, medicinal chemistry
Divisions:	Faculty of Science and Engineering > School of Physical Sciences
Depositing User:	Symplectic Admin
Date Deposited:	23 Dec 2022 14:20
Last Modified:	17 Mar 2024 15:40
DOI:	10.3762/bjoc.17.126
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3166788