Seroprevalence and Risk Factors for Q fever (Coxiella burnetii) Exposure in Smallholder Dairy Cattle in Tanzania

Bwatota, Shedrack Festo, Shirima, Gabriel Mkilema, Hernandez-Castro, Luis E, Bronsvoort, Barend Mark de Clare, Wheelhouse, Nick, Mengele, Isaac Joseph, Motto, Shabani Kiyabo, Komwihangilo, Daniel Mushumbusi, Lyatuu, Eliamoni and Cook, Elizabeth Anne Jessie ORCID: 0000-0001-6081-8363 (2022) Seroprevalence and Risk Factors for Q fever (Coxiella burnetii) Exposure in Smallholder Dairy Cattle in Tanzania. VETERINARY SCIENCES, 9 (12). 662-.

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Official URL: http://dx.doi.org/10.3390/vetsci9120662

Abstract

Q fever is a zoonotic disease, resulting from infection with Coxiella burnetii. Infection in cattle can cause abortion and infertility, however, there is little epidemiological information regarding the disease in dairy cattle in Tanzania. Between July 2019 and October 2020, a serosurvey was conducted in six high dairy producing regions of Tanzania. Cattle sera were tested for antibodies to C. burnetii using an indirect enzyme-linked immunosorbent assay. A mixed effect logistic regression model identified risk factors associated with C. burnetii seropositivity. A total of 79 out of 2049 dairy cattle tested positive with an overall seroprevalence of 3.9% (95% CI 3.06-4.78) across the six regions with the highest seroprevalence in Tanga region (8.21%, 95% CI 6.0-10.89). Risk factors associated with seropositivity included: extensive feeding management (OR 2.77, 95% CI 1.25-3.77), and low precipitation below 1000 mm (OR 2.76, 95% 1.37-7.21). The disease seroprevalence is relatively low in the high dairy cattle producing regions of Tanzania. Due to the zoonotic potential of the disease, future efforts should employ a "One Health" approach to understand the epidemiology, and for interdisciplinary control to reduce the impacts on animal and human health.

Item Type:	Article
Uncontrolled Keywords:	Q fever, coxiellosis, Coxiella burnetii, seroprevalence, dairy cattle, Tanzania
Divisions:	Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Infection, Veterinary and Ecological Sciences
Depositing User:	Symplectic Admin
Date Deposited:	31 Jan 2023 12:29
Last Modified:	18 Oct 2023 14:31
DOI:	10.3390/vetsci9120662
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3168017