An Explainable AI-Enabled Framework for Interpreting Pulmonary Diseases from Chest Radiographs



Naz, Zubaira, Khan, Muhammad Usman Ghani, Saba, Tanzila, Rehman, Amjad, Nobanee, Haitham ORCID: 0000-0003-4424-5600 and Bahaj, Saeed Ali
(2023) An Explainable AI-Enabled Framework for Interpreting Pulmonary Diseases from Chest Radiographs. CANCERS, 15 (1). 314-.

Access the full-text of this item by clicking on the Open Access link.

Abstract

Explainable Artificial Intelligence is a key component of artificially intelligent systems that aim to explain the classification results. The classification results explanation is essential for automatic disease diagnosis in healthcare. The human respiration system is badly affected by different chest pulmonary diseases. Automatic classification and explanation can be used to detect these lung diseases. In this paper, we introduced a CNN-based transfer learning-based approach for automatically explaining pulmonary diseases, i.e., edema, tuberculosis, nodules, and pneumonia from chest radiographs. Among these pulmonary diseases, pneumonia, which COVID-19 causes, is deadly; therefore, radiographs of COVID-19 are used for the explanation task. We used the ResNet50 neural network and trained the network on extensive training with the COVID-CT dataset and the COVIDNet dataset. The interpretable model LIME is used for the explanation of classification results. Lime highlights the input image's important features for generating the classification result. We evaluated the explanation using radiologists' highlighted images and identified that our model highlights and explains the same regions. We achieved improved classification results with our fine-tuned model with an accuracy of 93% and 97%, respectively. The analysis of our results indicates that this research not only improves the classification results but also provides an explanation of pulmonary diseases with advanced deep-learning methods. This research would assist radiologists with automatic disease detection and explanations, which are used to make clinical decisions and assist in diagnosing and treating pulmonary diseases in the early stage.

Item Type: Article
Uncontrolled Keywords: explainable AI, class activation map, Grad-CAM, LIME, coronavirus disease, reverse transcription polymerase chain reaction, computed tomography, healthcare, health risks
Divisions: Faculty of Humanities and Social Sciences > School of Histories, Languages and Cultures
Depositing User: Symplectic Admin
Date Deposited: 13 Feb 2023 09:34
Last Modified: 13 Feb 2023 09:34
DOI: 10.3390/cancers15010314
Open Access URL: https://doi.org/10.3390/cancers15010314
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3168377