Planar chromatography - Current practice and future prospects

Wilson, Ian D ORCID: 0000-0002-8558-7394 and Poole, Colin F (2023) Planar chromatography - Current practice and future prospects. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1214. 123553-.

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Abstract

Planar chromatography, in the form of thin-layer or high-performance thin-layer chromatography (TLC, HPTLC), continues to provide a robust and widely used separation technique. It is unrivaled as a simple and rapid qualitative method for mixture analysis, or for finding bioactive components in mixtures. The format of TLC/HPTLC also provides a unique method for preserving the separation, enabling further investigation of components of interest (including quantification/structure determination) separated in both time and space from the original analysis. The current practice of planar chromatography and areas of development of the technology are reviewed and promising future directions in the use of TLC/HPTLC are outlined.

Item Type:	Article
Uncontrolled Keywords:	TLC, HPTLC, MS, Automation, Effect-directed detection, Imaging
Divisions:	Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Systems, Molecular and Integrative Biology
Depositing User:	Symplectic Admin
Date Deposited:	24 Feb 2023 15:17
Last Modified:	24 Feb 2023 15:17
DOI:	10.1016/j.jchromb.2022.123553
Open Access URL:	https://doi.org/10.1016/j.jchromb.2022.123553
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3168588