Management of Bacterial and Fungal Infections in the ICU: Diagnosis, Treatment, and Prevention Recommendations

Rawson, Timothy M ORCID: 0000-0002-2630-9722, Antcliffe, David B, Wilson, Richard C ORCID: 0000-0002-3275-6932, Abdolrasouli, Alireza and Moore, Luke SP (2023) Management of Bacterial and Fungal Infections in the ICU: Diagnosis, Treatment, and Prevention Recommendations. INFECTION AND DRUG RESISTANCE, 16. pp. 2709-2726.

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Official URL: http://dx.doi.org/10.2147/idr.s390946

Abstract

Bacterial and fungal infections are common issues for patients in the intensive care unit (ICU). Large, multinational point prevalence surveys have identified that up to 50% of ICU patients have a diagnosis of bacterial or fungal infection at any one time. Infection in the ICU is associated with its own challenges. Causative organisms often harbour intrinsic and acquired mechanisms of drug-resistance, making empiric and targeted antimicrobial selection challenging. Infection in the ICU is associated with worse clinical outcomes for patients. We review the epidemiology of bacterial and fungal infection in the ICU. We discuss risk factors for acquisition, approaches to diagnosis and management, and common strategies for the prevention of infection.

Item Type:	Article
Uncontrolled Keywords:	bacterial infection, fungal infection, critical care, diagnostics, therapeutics
Divisions:	Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Systems, Molecular and Integrative Biology
Depositing User:	Symplectic Admin
Date Deposited:	12 May 2023 14:24
Last Modified:	10 Jun 2023 16:08
DOI:	10.2147/IDR.S390946
Open Access URL:	https://www.tandfonline.com/doi/full/10.2147/IDR.S...
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3170304