Immunological and translational key challenges in systemic lupus erythematosus: A symposium update



Renaudineau, Yves, Muller, Sylviane, Hedrich, Christian M ORCID: 0000-0002-1295-6179, Chauveau, Dominique, Belliere, Julie, De Almeida, Sebastien, Damoiseaux, Jan, Scherlinger, Marc, Guery, Jean Charles, Sailler, Laurent
et al (show 1 more authors) (2023) Immunological and translational key challenges in systemic lupus erythematosus: A symposium update. , Netherlands.

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Abstract

The first LBMR-Tim (Toulouse Referral Medical Laboratory of Immunology) symposium convened on December 16, 2022 in Toulouse, France to address challenging questions in systemic lupus erythematosus (SLE). Special focus was put on (i) the role played by genes, sex, TLR7, and platelets on SLE pathophysiology; (ii) autoantibodies, urinary proteins, and thrombocytopenia contribution at the time of diagnosis and during follow-up; (iii) neuropsychiatric involvement, vaccine response in the COVID-19 era, and lupus nephritis management at the clinical frontline; and (iv) therapeutic perspectives in patients with lupus nephritis and the unexpected adventure of the Lupuzor/P140 peptide. The multidisciplinary panel of experts further supports the concept that a global approach including basic sciences, translational research, clinical expertise, and therapeutic development have to be prioritized in order to better understand and then improve the management of this complex syndrome.

Item Type: Conference or Workshop Item (Unspecified)
Uncontrolled Keywords: Systemic lupus erythematosus, Genetics, TLR7, Platelets, Vaccine, COVID-19, Lupus nephritis, Nervous system, Lupuzor
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences
Depositing User: Symplectic Admin
Date Deposited: 17 May 2023 13:33
Last Modified: 22 Sep 2023 16:26
DOI: 10.1016/j.jtauto.2023.100199
Open Access URL: https://doi.org/10.1016/j.jtauto.2023.100199
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3170433