Ahmed, Mahmoud, Krishna, Yamini 
ORCID: 0000-0001-5067-3682, Popova, Petya, Herbert, Rose, Sidaras, Gediminas, Choudhary, Anshoo and Kaye, Stephen BB ORCID: 0000-0003-0390-0592
(2023)
Low-Dose Propofol with Peribulbar Anaesthesia for Cataract Surgery.
JOURNAL OF CLINICAL MEDICINE, 12 (7).
2742-.
|
PDF
Low-Dose Propofol with Peribulbar Anaesthesia for Cataract Surgery.pdf - Open Access published version Download (400kB) | Preview |
Abstract
In this paper, we investigate the effect of sedation using low-dose propofol on patient reported outcome measures (PROMS) in patients undergoing cataract surgery. This is a randomised, single-blinded observational prospective study. Patients undergoing elective cataract surgery using peribulbar anaesthesia over consecutive cataract lists were selected for this trial. Patients were randomised to receive either no sedation or low-dose propofol (20 to 30 mg followed by 10 mg increments until the patient developed slurred speech alone) prior to the administration of local anaesthesia. Pain, satisfaction, anxiety, needle recall, pulse, and blood pressure (BP) were measured. A total of 97 patients were included, 50 of whom received propofol. There were 4 senior surgeons and anaesthetists. There were no ocular or systemic complications and all patients had uncomplicated surgery. Anxiety (<i>p</i> = 0.026), needle recall (<i>p</i> < 0.001), difference in systolic BP (<i>p</i> = 0.043), and pulse (<i>p</i> = 0.046) were dependent on patient age (<i>p</i> < 0.001) and the use of propofol (<i>p</i> = 0.007). Lower pain was associated with propofol (<i>p</i> = 0.008), as well as lower anxiety (<i>p</i> = 0.002), and increased patient age (<i>p</i> = 0.014). The administration of propofol was significantly associated with lower needle recall (<i>p</i> < 0.001), pre- to post-operative difference in systolic BP (<i>p</i> = 0.029), and mean BP (<i>p</i> = 0.044). Low-dose propofol given immediately prior to administration of local anaesthesia was associated with reduced pain and needle recall, as well as lower BP.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | PROMS, anaesthesia, sedation, cataract surgery, propofol |
| Divisions: | Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences Faculty of Health and Life Sciences > Institute of Systems, Molecular and Integrative Biology |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 19 May 2023 09:12 |
| Last Modified: | 19 May 2023 09:13 |
| DOI: | 10.3390/jcm12072742 |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3170536 |
Dimensions
Dimensions
