Equine Endocrine Disease: Challenges With Case Definition for Research

McGowan, Catherine M ORCID: 0000-0002-1946-9584 and Ireland, Joanne L ORCID: 0000-0002-5737-1502 (2023) Equine Endocrine Disease: Challenges With Case Definition for Research. Journal of Equine Veterinary Science, 124. p. 104491.

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Abstract

Equine endocrine disease is an important area for equine research, requiring an appropriate case definition for inclusion and criteria for exclusion from disease. Defining a case for research may be different from criteria for clinical diagnosis. Further, clinical diagnosis recommendations have been changing regularly, making this area challenging for equine scientists. This review discusses the diagnosis of major equine endocrine diseases, pituitary pars intermedia dysfunction, equine metabolic syndrome and insulin dysregulation, focusing on the most appropriate diagnostic methods for research case definitions. Different diagnostic methods, including use of reference intervals and clinical decision limits, will be discussed with their relative merits for use in case definition for research.

Item Type:	Article
Uncontrolled Keywords:	Animals, Horses, Pituitary Diseases, Endocrine System Diseases, Horse Diseases, Insulin, Metabolic Syndrome
Divisions:	Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Infection, Veterinary and Ecological Sciences
Depositing User:	Symplectic Admin
Date Deposited:	30 May 2023 07:28
Last Modified:	10 Jun 2023 01:16
DOI:	10.1016/j.jevs.2023.104491
Open Access URL:	https://doi.org/10.1016/j.jevs.2023.104491
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3170716