Association between socioeconomic deprivation and incidence of Infectious Intestinal Disease by pathogen and linked transmission route: An ecological analysis in the UK

Buczkowska, Matylda, Butt, Saira, Jenkins, Claire, Hungerford, Daniel ORCID: 0000-0002-9770-0163, Hawker, Jeremy, Verlander, Neville Q, O’Connell, Anne-Marie and Byrne, Lisa (2023) Association between socioeconomic deprivation and incidence of Infectious Intestinal Disease by pathogen and linked transmission route: An ecological analysis in the UK. Epidemiology and Infection, 151. e109-.

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Official URL: https://doi.org/10.1017/S0950268823000869

Abstract

Infectious intestinal disease (IID) studies conducted at different levels of the surveillance pyramid have found heterogeneity in the association of socioeconomic deprivation with illness. The aim of this study was to analyse the association between socioeconomic deprivation and incidence of IID by certain gastrointestinal pathogens reported to UKHSA. Data were extracted from 2015 to 2018 for Salmonella, Campylobacter, Shigella, Giardia species, and norovirus. Rates were calculated per 100,000 person-years by the index of multiple deprivation quintile, and an ecological analysis was conducted using univariant and multvariable regression models for each pathogen. Incidence of Campylobacter, and Giardia species decreased with increasing deprivation. Conversely, the incidence of norovirus, non-typhoidal Salmonella, Salmonella typhi/paratyphi, Shigella species increased with increasing deprivation. Multivariable analysis results showed that higher deprivation was significantly associated with higher odds of higher number of cases for Shigella flexneri, norovirus and S. typhi/paratyphi. Infections most associated with deprivation were those transmitted by person-to-person spread, and least associated were those transmitted by zoonotic contamination of the environment. Person-to-person transmission can be contained by implementing policies targeting over-crowding and poor hygiene. This approach is likely to be the most effective solution for the reduction of IID.

Item Type:	Article
Uncontrolled Keywords:	deprivation, ecological analysis, gastrointestinal disease, incidence, inequalities, infectious intestinal disease, laboratory data, surveillance, transmission route
Divisions:	Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Infection, Veterinary and Ecological Sciences
Depositing User:	Symplectic Admin
Date Deposited:	14 Jun 2023 08:39
Last Modified:	11 Oct 2023 14:38
DOI:	10.1017/S0950268823000869
Open Access URL:	https://www.cambridge.org/core/journals/epidemiolo...
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3170998