Global Landscape of Encephalitis: Key Priorities to Reduce Future Disease Burden



Granerod, Julia, Huang, Yun, Davies, Nicholas WS, Sequeira, Patricia C, Mwapasa, Victor, Rupali, Priscilla, Michael, Benedict D ORCID: 0000-0002-8693-8926, Solomon, Tom ORCID: 0000-0001-7266-6547 and Easton, Ava
(2023) Global Landscape of Encephalitis: Key Priorities to Reduce Future Disease Burden. CLINICAL INFECTIOUS DISEASES, 77 (11). pp. 1552-1560.

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Abstract

Encephalitis affects people across the lifespan, has high rates of mortality and morbidity, and results in significant neurological sequelae with long-term consequences to quality of life and wider society. The true incidence is currently unknown due to inaccurate reporting systems. The disease burden of encephalitis is unequally distributed across the globe being highest in low- and middle-income countries where resources are limited. Here countries often lack diagnostic testing, with poor access to essential treatments and neurological services, and limited surveillance and vaccination programs. Many types of encephalitis are vaccine preventable, whereas others are treatable with early diagnosis and appropriate management. In this viewpoint, we provide a narrative review of key aspects of diagnosis, surveillance, treatment, and prevention of encephalitis and highlight priorities for public health, clinical management, and research, to reduce the disease burden.

Item Type: Article
Uncontrolled Keywords: encephalitis, treatment, diagnosis, burden, vaccination
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Infection, Veterinary and Ecological Sciences
Depositing User: Symplectic Admin
Date Deposited: 21 Jul 2023 15:09
Last Modified: 22 Jan 2024 10:19
DOI: 10.1093/cid/ciad417
Open Access URL: https://academic.oup.com/cid/advance-article/doi/1...
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3171825