Chen, Robert, Berardelli, Alfredo, Bhattacharya, Amitabh, Bologna, Matteo, Chen, Kai-Hsiang Stanley, Fasano, Alfonso, Helmich, Rick C, Hutchison, William D, Kamble, Nitish, Kuehn, Andrea A et al (show 6 more authors)
(2022)
Clinical neurophysiology of Parkinson's disease and parkinsonism.
CLINICAL NEUROPHYSIOLOGY PRACTICE, 7.
pp. 201-227.
Text
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Abstract
This review is part of the series on the clinical neurophysiology of movement disorders. It focuses on Parkinson's disease and parkinsonism. The topics covered include the pathophysiology of tremor, rigidity and bradykinesia, balance and gait disturbance and myoclonus in Parkinson's disease. The use of electroencephalography, electromyography, long latency reflexes, cutaneous silent period, studies of cortical excitability with single and paired transcranial magnetic stimulation, studies of plasticity, intraoperative microelectrode recordings and recording of local field potentials from deep brain stimulation, and electrocorticography are also reviewed. In addition to advancing knowledge of pathophysiology, neurophysiological studies can be useful in refining the diagnosis, localization of surgical targets, and help to develop novel therapies for Parkinson's disease.
Item Type: | Article |
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Uncontrolled Keywords: | Bradykinesia, Deep brain stimulation, Electroencephalography, Electromyography, Gait and balance, Local field potentials, Long latency reflexes, Microelectrode recording, Transcranial magnetic stimulation, Tremor |
Divisions: | Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Systems, Molecular and Integrative Biology |
Depositing User: | Symplectic Admin |
Date Deposited: | 09 Oct 2023 07:24 |
Last Modified: | 09 Oct 2023 07:24 |
DOI: | 10.1016/j.cnp.2022.06.002 |
Related URLs: | |
URI: | https://livrepository.liverpool.ac.uk/id/eprint/3173517 |