Overton, Christopher E 
ORCID: 0000-0002-8433-4010, Stage, Helena B, Ahmad, Shazaad, Curran-Sebastian, Jacob, Dark, Paul, Das, Rajenki, Fearon, Elizabeth, Felton, Timothy, Fyles, Martyn, Gent, Nick et al (show 9 more authors)
(2020)
Using statistics and mathematical modelling to understand infectious disease outbreaks: COVID-19 as an example.
INFECTIOUS DISEASE MODELLING, 5.
pp. 409-441.
Abstract
During an infectious disease outbreak, biases in the data and complexities of the underlying dynamics pose significant challenges in mathematically modelling the outbreak and designing policy. Motivated by the ongoing response to COVID-19, we provide a toolkit of statistical and mathematical models beyond the simple SIR-type differential equation models for analysing the early stages of an outbreak and assessing interventions. In particular, we focus on parameter estimation in the presence of known biases in the data, and the effect of non-pharmaceutical interventions in enclosed subpopulations, such as households and care homes. We illustrate these methods by applying them to the COVID-19 pandemic.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Bias, COVID-19, Epidemic modelling, Intervention, Outbreak, Parameter estimation |
| Divisions: | Faculty of Science and Engineering > School of Physical Sciences |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 16 Oct 2023 08:15 |
| Last Modified: | 16 Oct 2023 08:15 |
| DOI: | 10.1016/j.idm.2020.06.008 |
| Open Access URL: | https://doi.org/10.1016/j.idm.2020.06.008 |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3173733 |
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