Novel contributions to understanding the mechanism of folate transport and anti-folate resistance in Plasmodium falciparum



Omondi Ochong, Edwin
(2008) Novel contributions to understanding the mechanism of folate transport and anti-folate resistance in Plasmodium falciparum. PhD thesis, University of Liverpool.

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Abstract

The primary focus of the PhD thesis has exclusively been on studies on Plasmodium falciparum with a remit to build a clear understanding on some of the critical and relevant questions relating to folates transport and antifolates resistance. The direction of this work has been constructed on the following themes of interest; 1. The Influence of folate pathway substrates on the In Vitro activities of antifolate drugs. 2. Functional characterization of heterologously expressed putative folate transporters in the Xenopus laevis oocyte. 3. Transcriptional analysis of putative folate transporter genes.

Item Type: Thesis (PhD)
Depositing User: Symplectic Admin
Date Deposited: 20 Oct 2023 09:25
Last Modified: 20 Oct 2023 09:29
DOI: 10.17638/03174578
Copyright Statement: Copyright © and Moral Rights for this thesis and any accompanying data (where applicable) are retained by the author and/or other copyright owners. A copy can be downloaded for personal non-commercial research or study, without prior permission or charge
URI: https://livrepository.liverpool.ac.uk/id/eprint/3174578