A goat eye, wet lab model for training in Descemet membrane endothelial keratoplasty



Gupta, Nidhi, Bhogal, Maninder, Vaddavalli, Pravin K, Boldini, Alessandro, Semeraro, Francesco, Varshney, Akhil and Romano, Vito ORCID: 0000-0002-5148-7643
(2023) A goat eye, wet lab model for training in Descemet membrane endothelial keratoplasty. INDIAN JOURNAL OF OPHTHALMOLOGY, 71 (5). pp. 2230-2233.

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Abstract

Here we describe a new, non-human, ex-vivo model (goat eye model) for training surgeons in DMEK surgeons. In a wet lab setting, goat eyes were used to obtain a pseudo-DMEK graft of 8 mm from the goat lens capsule that was injected into another goat eye with the same maneuvers described for human DMEK. The DMEK pseudo-graft can be easily prepared, stained, loaded, injected, and unfolded into the goat eye model reproducing the similar maneuvers used for DMEK in a human eye, except for the descemetorhexis, which cannot be performed. The pseudo-DMEK graft behaves similar to human DMEK graft and useful for surgeons to experience and understand steps of DMEK early in learning curve. The concept of a non-human ex-vivo eye model is simple and reproducible and obviates the need for human tissue and the issues of poor visibility in stored corneal tissue.

Item Type: Article
Uncontrolled Keywords: DMEK, learning curve, non-human model, training, wet lab
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences
Depositing User: Symplectic Admin
Date Deposited: 30 Nov 2023 16:54
Last Modified: 30 Nov 2023 16:54
DOI: 10.4103/ijo.IJO_1834_22
Open Access URL: https://journals.lww.com/ijo/fulltext/2023/05000/a...
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3177118