Case Report: "Spontaneous Descemet Membrane Detachment"

Moramarco, Antonio, Iannetta, Danilo, Cimino, Luca, Romano, Vito ORCID: 0000-0002-5148-7643, Gardini, Lorenzo and Fontana, Luigi (2023) Case Report: "Spontaneous Descemet Membrane Detachment". JOURNAL OF CLINICAL MEDICINE, 12 (1). 330-.

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Official URL: http://dx.doi.org/10.3390/jcm12010330

Abstract

<h4>Introduction</h4>We report a case and discuss the clinical characteristics and treatment of spontaneous Descemet membrane detachment (DMD).<h4>Case description</h4>We describe a rare case of spontaneous DMD in a patient with prior anterior uveitis and provide a review of the current literature. A 20-year-old woman with a prior history of anterior uveitis presented with vision loss in the left eye. The slit-lamp examination showed corneal edema secondary to DMD, confirmed by anterior segment optical coherence tomography (AS-OCT). The patient underwent an intracameral injection of 20% sulphur hexafluoride (SF<sub>6</sub>) with complete resolution of the DMD. Although rare, several cases of spontaneous DMD have been reported in the literature, mostly occurring after intraocular surgery. We searched the Pubmed database (1949-2021) for peer-reviewed publications relevant to the topic of spontaneous DMD.<h4>Discussion</h4>The pathogenesis of spontaneous DMD is complex and depends on several factors. It can occur due to anatomical anomalies, inflammatory disease, trauma, chemical injuries, and surgical or laser procedures. In most cases, early diagnosis and appropriate management led to resolution.

Item Type:	Article
Uncontrolled Keywords:	Descemet membrane detachment, anterior uveitis, anterior segment optical coherence tomography, sulphur hexafluoride, corneal edema
Divisions:	Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences
Depositing User:	Symplectic Admin
Date Deposited:	14 Dec 2023 09:16
Last Modified:	14 Dec 2023 09:21
DOI:	10.3390/jcm12010330
Open Access URL:	https://doi.org/10.3390/jcm12010330
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3177379