Assessment of mortality from COVID-19 in a multicultural multi-ethnic patient population.



Nair, Satish Chandrasekhar, Gasmelseed, Huda Imam, Khan, Asad Afroz, Khafagy, Ibrahim Nageh, Sreedharan, Jayadevan, Saleem, Aqeel Aziz, Abdrhman, Hashim Ibrahim, Alhosani, Ahmed Husain, Siddiqua, Amatur Rahman, Ahmed, Amna Riaz
et al (show 14 more authors) (2021) Assessment of mortality from COVID-19 in a multicultural multi-ethnic patient population. BMC infectious diseases, 21 (1). p. 1115.

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Abstract

<h4>Background</h4>Studies indicate that ethnicity and socioeconomic disparity are significant facilitators for COVID-19 mortality. The United Arab Emirates, distinctly has a population of almost 12% citizens and the rest, immigrants, are mainly unskilled labourers. The disparate socio-economic structure, crowded housing conditions, and multi-ethnic population offer a unique set of challenges in COVID-19 management.<h4>Methods</h4>Patient characteristics, comorbidities, and clinical outcomes data from the electronic patient medical records were retrospectively extracted from the hospital information system of the two designated public COVID-19 referral hospitals. Chi-square test, logistic regression, and odds ratio were used to analyse the variables.<h4>Results</h4>From, the total of 3072 patients, less than one-fifth were females; the Asian population (71.2%);followed by Middle Eastern Arabs (23.3%) were the most infected by the virus. Diabetes Mellitus (26.8%), hypertension (25.7%) and heart disease (9.6%) were the most prevalent comorbidities observed among COVID-19 patients. Kidney disease as comorbidity significantly diminished the survival rates (Crude OR 9.6, 95% CI (5.6-16.6), p < 0.001) and (Adjusted OR 5.7 95% CI (3.0 - 10.8), p < 0.001), as compared to those patients without kidney disease. Similarly, the higher age of patients between 51 and 65 years, significantly decreased the odds for survival (Crude OR 14.1 95% CI (3.4-58.4), p < 0.001) and (Adjusted OR 12.3 95% CI (2.9 - 52.4), p < 0.001). Patient age beyond 66 years, further significantly decreased the odds for survival (Crude OR 36.1 95% CI (8.5-154.1), p < 0.001), and (Adjusted OR 26.6 95% CI (5.7 - 123.8), p < 0.001).<h4>Conclusion</h4>Our study indicates that older ages above 51 years and kidney disease increased mortality significantly in COVID-19 patients. Ethnicity was not significantly associated with mortality in the UAE population. Our findings are important in the management of the COVID-19 disease in the region with similar economic, social, cultural, and ethnic backgrounds.

Item Type: Article
Uncontrolled Keywords: Humans, Hospitalization, Hospital Mortality, Risk Factors, Retrospective Studies, Comorbidity, Aged, Middle Aged, Female, COVID-19, SARS-CoV-2, Ethnicity
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences
Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences > School of Medicine
Depositing User: Symplectic Admin
Date Deposited: 15 Dec 2023 09:46
Last Modified: 15 Dec 2023 09:46
DOI: 10.1186/s12879-021-06762-9
Open Access URL: https://doi.org/10.1186/s12879-021-06762-9
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3177405