Could dietary restrictions affect periodontal disease? A systematic review

Mainas, Giuseppe, Santamaria, Pasquale, Ide, Mark, Longo, Valter, Vinciguerra, Manlio ORCID: 0000-0002-1768-3894, Nart, Jose and Nibali, Luigi (2023) Could dietary restrictions affect periodontal disease? A systematic review. CLINICAL ORAL INVESTIGATIONS, 27 (8). pp. 4107-4116.

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Abstract

<h4>Objective</h4>This review aimed at evaluating the possible benefits that caloric restriction (CR) may provide to periodontal disease progression and response to treatment.<h4>Material and methods</h4>Electronic search on Medline, Embase and Cochrane, and manual search were performed to identify pre-clinical and on human studies reporting the consequences of CR on clinical and inflammatory parameters related to periodontitis. Newcastle Ottawa System and SYRCLE scale were used to assess the risk of bias.<h4>Results</h4>Four thousand nine hundred eighty articles were initially screened, and a total of 6 articles were finally included, consisting of 4 animal studies and 2 studies in humans. Due to the limited number of studies and heterogeneity of the data, results were presented in descriptive analyses. All studies showed that, compared to the normal (ad libitum) diet, CR might have the potential to reduce the local and systemic hyper-inflammatory state as well as disease progression in periodontal patients.<h4>Conclusions</h4>Within the existing limitations, this review highlights that CR showed some improvements in the periodontal condition by reducing the local and systemic inflammation related to the periodontitis and by improving clinical parameters. However, the results should be interpreted with caution since robust research such as randomized clinical trials is still missing.<h4>Clinical relevance</h4>This review shows that some dietary/caloric restrictions approaches may have the potential to improve periodontal conditions and, in addition, highlights a need for human studies with a robust methodology in order to draw stronger evidence-based conclusions.

Item Type:	Article
Uncontrolled Keywords:	Caloric restriction, Diet, Fasting, Inflammation, Periodontitis, Systematic review
Divisions:	Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences
Depositing User:	Symplectic Admin
Date Deposited:	15 Dec 2023 10:56
Last Modified:	15 Dec 2023 10:57
DOI:	10.1007/s00784-023-05052-9
Open Access URL:	https://doi.org/10.1007/s00784-023-05052-9
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3177430