Dawson, Camilla, Clunie, Gemma, Evison, Felicity, Duncan, Sallyanne, Whitney, Julie, Houchen-Wolloff, Linzy, Bolton, Charlotte E, Leavy, Olivia C, Richardson, Matthew, Omer, Elneima et al (show 39 more authors)
(2023)
Prevalence of swallow, communication, voice and cognitive compromise following hospitalisation for COVID-19: the PHOSP-COVID analysis.
BMJ OPEN RESPIRATORY RESEARCH, 10 (1).
e001647-.
Abstract
<h4>Objective</h4>Identify prevalence of self-reported swallow, communication, voice and cognitive compromise following hospitalisation for COVID-19.<h4>Design</h4>Multicentre prospective observational cohort study using questionnaire data at visit 1 (2-7 months post discharge) and visit 2 (10-14 months post discharge) from hospitalised patients in the UK. Lasso logistic regression analysis was undertaken to identify associations.<h4>Setting</h4>64 UK acute hospital Trusts.<h4>Participants</h4>Adults aged >18 years, discharged from an admissions unit or ward at a UK hospital with COVID-19.<h4>Main outcome measures</h4>Self-reported swallow, communication, voice and cognitive compromise.<h4>Results</h4>Compromised swallowing post intensive care unit (post-ICU) admission was reported in 20% (188/955); 60% with swallow problems received invasive mechanical ventilation and were more likely to have undergone proning (p=0.039). Voice problems were reported in 34% (319/946) post-ICU admission who were more likely to have received invasive (p<0.001) or non-invasive ventilation (p=0.001) and to have been proned (p<0.001). Communication compromise was reported in 23% (527/2275) univariable analysis identified associations with younger age (p<0.001), female sex (p<0.001), social deprivation (p<0.001) and being a healthcare worker (p=0.010). Cognitive issues were reported by 70% (1598/2275), consistent at both visits, at visit 1 respondents were more likely to have higher baseline comorbidities and at visit 2 were associated with greater social deprivation (p<0.001).<h4>Conclusion</h4>Swallow, communication, voice and cognitive problems were prevalent post hospitalisation for COVID-19, alongside whole system compromise including reduced mobility and overall health scores. Research and testing of rehabilitation interventions are required at pace to explore these issues.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | ARDS, COVID-19, critical care, pneumonia |
| Divisions: | Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Infection, Veterinary and Ecological Sciences |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 02 Feb 2024 10:30 |
| Last Modified: | 02 Feb 2024 10:30 |
| DOI: | 10.1136/bmjresp-2023-001647 |
| Open Access URL: | https://bmjopenrespres.bmj.com/content/10/1/e00164... |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3178298 |
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