Evans, Sharon, Ashmore, Catherine, Daly, Anne, Jackson, Richard, Pinto, Alex and MacDonald, Anita
(2022)
Validation of a Low-protein Semi-Quantitative Food Frequency Questionnaire.
NUTRIENTS, 14 (8).
1595-.
Abstract
Analysis of dietary patterns and their role in long-term health is limited in phenylketonuria (PKU). Food frequency questionnaires (FFQ) are commonly used to assess habitual intake. A semi-quantitative 89-item FFQ with a portion size photographic booklet was developed for children with PKU as a tool for collecting data on habitual intake of foods, food groups, energy and macronutrient intake. Twenty children with PKU aged 11−16 years, 30 parents of children with PKU aged 4−10 years, and 50 age/gender-matched control children were recruited. To test reproducibility, FFQs were completed twice with a mean interval of 5 weeks (range: 4−10). In order to test validity, FFQs were compared with five 24-h dietary recalls with a mean interval of 10 days (range: 6−18). Energy and macronutrient intake and quantity/week of individual food items were calculated and compared. There was good reproducibility for the FFQ with macronutrient correlations r > 0.6 and good validity data with most correlations r > 0.5. Bland−Altman plots for reproducibility and validity showed mean levels close to 0 and usually within 2 standard deviations. FFQ comparisons of PKU and control groups identified expected differences in % energy from macronutrients (PKU vs. control: carbohydrate 59% vs. 51%, fat 26% vs. 33%, protein 15% vs. 16%). This FFQ for PKU produced comparable data to repeated dietary recalls and is a valid tool for collecting data on habitual food and nutrient intake. It will be useful in assessing changes in dietary phenylalanine tolerance of new pharmacological treatments for PKU.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | dietary patterns, food frequency questionnaire, phenylketonuria (PKU), reproducibility, validation |
| Divisions: | Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Population Health |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 02 Feb 2024 11:39 |
| Last Modified: | 02 Feb 2024 11:39 |
| DOI: | 10.3390/nu14081595 |
| Open Access URL: | https://doi.org/10.3390/nu14081595 |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3178359 |
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