Intrinsic Cardiac Neuromodulation in the Management of Atrial Fibrillation- A Potential Missing Link?

Aksu, Tolga, Gupta, Dhiraj ORCID: 0000-0002-3490-090X, Skeete, Jamario R and Huang, Henry H (2024) Intrinsic Cardiac Neuromodulation in the Management of Atrial Fibrillation- A Potential Missing Link? LIFE-BASEL, 13 (2). 383-.

Access the full-text of this item by clicking on the Open Access link.

Official URL: http://dx.doi.org/10.3390/life13020383

Abstract

Atrial fibrillation (AF) is the most common supraventricular arrhythmia that is linked with higher cardiovascular morbidity and mortality. Recent evidence has demonstrated that catheter-based pulmonary vein isolation (PVI) is not only a viable alternative but may be superior to antiarrhythmic drug therapy for long-term freedom from symptomatic AF episodes, a reduction in the arrhythmia burden, and healthcare resource utilization with a similar risk of adverse events. The intrinsic cardiac autonomic nervous system (ANS) has a significant influence on the structural and electrical milieu, and imbalances in the ANS may contribute to the arrhythmogenesis of AF in some individuals. There is now increasing scientific and clinical interest in various aspects of neuromodulation of intrinsic cardiac ANS, including mapping techniques, ablation methods, and patient selection. In the present review, we aimed to summarize and critically appraise the currently available evidence for the neuromodulation of intrinsic cardiac ANS in AF.

Item Type:	Article
Uncontrolled Keywords:	atrial fibrillation, autonomic nervous system, cardioneuroablation, ganglionated plexus
Divisions:	Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences
Depositing User:	Symplectic Admin
Date Deposited:	06 Feb 2024 09:39
Last Modified:	06 Feb 2024 09:39
DOI:	10.3390/life13020383
Open Access URL:	https://doi.org/10.3390/life13020383
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3178418