Gomersall, Jenny, Mortimer, Kalani, Hassan, Deniz, Whitehead, Kathryn A, Slate, Anthony J, Ryder, Steven F, Chambers, Lucy E, El Mohtadi, Mohamed and Shokrollahi, Kayvan ORCID: 0000-0003-1044-7781
(2023)
Ten-Year Analysis of Bacterial Colonisation and Outcomes of Major Burn Patients with a Focus on <i>Pseudomonas aeruginosa</i>.
Microorganisms, 12 (1).
p. 42.
Abstract
A retrospective descriptive study included patients admitted with severe burns over the course of 10 years (2008-2018). Across all patients, there were 39 different species of bacteria, with 23 species being Gram-negative and 16 being Gram-positive bacteria, with also five different species of fungi cultured. <i>Pseudomonas aeruginosa</i> was the most commonly isolated organism, with 57.45% of patients having a positive culture. There was a significant difference in the number of <i>P. aeruginosa</i> isolated from patients that acquired their burns at work, in a garden, inside a vehicle, in a garage or in a public place. In patients that were positive for <i>P. aeruginosa</i>, the number of operations was higher (2.4) and the length of stay was significantly increased (80.1 days). Patients that suffered from substance abuse demonstrated significantly higher numbers of isolated <i>P. aeruginosa</i> (14.8%). Patients that suffered from both mental health illness and substance abuse demonstrated significantly higher numbers of <i>P. aeruginosa</i> isolated (18.5%). In the <i>P. aeruginosa</i>-negative group, there were significantly fewer patients that had been involved in a clothing fire. Furthermore, in the <i>P. aeruginosa</i>-negative patient cohort, the mortality rate was significantly higher (<i>p</i> = 0.002). Since the incidence of <i>P. aeruginosa</i> was also associated with a decreased mortality rate, it may be that patients admitted to hospital for shorter periods of time were less likely to be colonised with <i>P. aeruginosa</i>. This study demonstrates novel factors that may increase the incidence of <i>P. aeruginosa</i> isolated from burn patients.
Item Type: | Article |
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Uncontrolled Keywords: | Pseudomonas aeruginosa, burns, environment, infection, mortality, polymicrobial |
Divisions: | Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences > School of Medicine |
Depositing User: | Symplectic Admin |
Date Deposited: | 06 Feb 2024 11:13 |
Last Modified: | 06 Feb 2024 11:13 |
DOI: | 10.3390/microorganisms12010042 |
Open Access URL: | https://doi.org/10.3390/microorganisms12010042 |
Related URLs: | |
URI: | https://livrepository.liverpool.ac.uk/id/eprint/3178464 |