The role of nutraceuticals in heart failure muscle wasting as a result of inflammatory activity. The International Lipid Expert Panel (ILEP) Position Paper



Bielecka-Dabrowa, Agata, Banach, Maciej, Wittczak, Andrzej, Cicero, Arrigo FG, Kallel, Amani, Kubilius, Raimondas, Mikhailidis, Dimitri P, Sahebkar, Amirhossein, Stoian, Anca Pantea, Vinereanu, Dragos
et al (show 3 more authors) (2023) The role of nutraceuticals in heart failure muscle wasting as a result of inflammatory activity. The International Lipid Expert Panel (ILEP) Position Paper. ARCHIVES OF MEDICAL SCIENCE, 19 (4). pp. 841-864.

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Abstract

Muscle wasting is one of the main causes for exercise intolerance and ventilatory inefficiency in patients with heart failure and a strong predictor of frailty and reduced survival. The prevalence of sarcopenia is at least 20% in patients with heart failure. Patients with heart failure often have subclinical systemic inflammation, which may exert sustained effects on skeletal muscle. Besides exercise, nutrition should also be carefully evaluated as an appropriate diet with selected nutraceuticals may be able to stimulate muscle anabolism and inhibit muscle catabolism. This review summarizes the epidemiological and clinical trial evidence supporting the recommendations for the use of nutraceuticals with anti-inflammatory properties in heart failure and provides an overview of the state of the evidence for nutraceutical supplementation to prevent and/or mitigate heart failure muscle wasting.

Item Type: Article
Uncontrolled Keywords: hand grip strength, heart failure, inflammation, muscle wasting, nutraceuticals, sarcopenia
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences
Depositing User: Symplectic Admin
Date Deposited: 06 Feb 2024 11:11
Last Modified: 06 Feb 2024 11:11
DOI: 10.5114/aoms/167799
Open Access URL: https://doi.org/10.5114/aoms/167799
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3178490