Guidance for the Interpretation of Long-Acting Cabotegravir and Rilpivirine Concentrations Based on Real-World Therapeutic Drug Monitoring Data and Documented Failures.

Thoueille, Paul ORCID: 0000-0002-2305-4277, Cavassini, Matthias ORCID: 0000-0003-0933-7833, Guidi, Monia ORCID: 0000-0002-6419-9317, Buclin, Thierry ORCID: 0000-0003-0639-5536, Girardin, François R, Decosterd, Laurent A ORCID: 0000-0002-9840-1325 and Marzolini, Catia ORCID: 0000-0002-2312-7050 (2024) Guidance for the Interpretation of Long-Acting Cabotegravir and Rilpivirine Concentrations Based on Real-World Therapeutic Drug Monitoring Data and Documented Failures. Open forum infectious diseases, 11 (2). ofae023-.

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Abstract

The interpretation of long-acting cabotegravir and rilpivirine concentrations is complicated by the lack of consensus on the threshold to consider. Building on real-world therapeutic drug monitoring data and documented virologic failures, this article provides a reappraisal of the existing thresholds and guidance for the interpretation of cabotegravir and rilpivirine concentrations.

Item Type:	Article
Uncontrolled Keywords:	TDM, cabotegravir, guidance, long-acting, rilpivirine
Divisions:	Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Systems, Molecular and Integrative Biology
Depositing User:	Symplectic Admin
Date Deposited:	29 Feb 2024 09:08
Last Modified:	29 Feb 2024 09:08
DOI:	10.1093/ofid/ofae023
Open Access URL:	https://doi.org/10.1093/ofid/ofae023
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3178987