Descemet membrane endothelial keratoplasty combined with presbyopia-correcting and toric intraocular lenses - a narrative review.



Rodríguez-Calvo-de-Mora, Marina, Rocha-de-Lossada, Carlos, Romano, Vito ORCID: 0000-0002-5148-7643, Rodríguez-Vallejo, Manuel and Fernández, Joaquín
(2023) Descemet membrane endothelial keratoplasty combined with presbyopia-correcting and toric intraocular lenses - a narrative review. BMC ophthalmology, 23 (1). p. 483.

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Abstract

Fuchs endothelial corneal dystrophy (FECD) is the leading indication for EK and may coexist with cataract and presbyopia. Notably, the outcomes of phacoemulsification in FECD patients are not as favorable as those in eyes without this condition. Historically, only monofocal intraocular lenses (IOLs) were recommended for these patients. However, recent reports have described the implantation of Premium-IOLs (such as Multifocal IOLs, Enhanced Depth of Focus IOLs, and Toric IOLs) in FECD eyes undergoing cataract surgery and Descemet membrane endothelial keratoplasty (DMEK). While the results are encouraging, they are not as optimal as those from unoperated eyes, especially when comparing simultaneous procedures to sequential ones. It's advised to perform the DMEK first to improve the accuracy of IOL calculations. Still, even successfully operated eyes may experience secondary graft failure or graft rejection after DMEK. The success rate of a secondary DMEK is typically lower than that of the initial procedure. Furthermore, if the postoperative thickness after DMEK is less than anticipated, laser enhancements might not be an option. There's a pressing need for more controlled and randomized clinical trials to ascertain the safety and effectiveness of Premium-IOLs for FECD eyes. This narrative review aims to collate evidence on the use of Premium IOL technologies in eyes receiving EK and to underscore key points for surgeons performing EK combined with cataract surgery.

Item Type: Article
Uncontrolled Keywords: Humans, Fuchs' Endothelial Dystrophy, Cataract, Presbyopia, Corneal Transplantation, Lens Implantation, Intraocular, Retrospective Studies, Lenses, Intraocular, Visual Acuity, Descemet Membrane, Descemet Stripping Endothelial Keratoplasty
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences
Depositing User: Symplectic Admin
Date Deposited: 01 Mar 2024 09:24
Last Modified: 01 Mar 2024 09:24
DOI: 10.1186/s12886-023-03240-5
Open Access URL: https://doi.org/10.1186/s12886-023-03240-5
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3179019