Atrial fibrillation: comorbidities, lifestyle, and patient factors.

Shantsila, Eduard ORCID: 0000-0002-2429-6980, Choi, Eue-Keun, Lane, Deirdre A ORCID: 0000-0002-5604-9378, Joung, Boyoung and Lip, Gregory YH ORCID: 0000-0002-7566-1626 (2024) Atrial fibrillation: comorbidities, lifestyle, and patient factors. The Lancet regional health. Europe, 37. p. 100784.

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Abstract

Modern anticoagulation therapy has dramatically reduced the risk of stroke and systemic thromboembolism in people with atrial fibrillation (AF). However, AF still impairs quality of life, increases the risk of stroke and heart failure, and is linked to cognitive impairment. There is also a recognition of the residual risk of thromboembolic complications despite anticoagulation. Hence, AF management is evolving towards a more comprehensive understanding of risk factors predisposing to the development of this arrhythmia, its' complications and interventions to mitigate the risk. This review summarises the recent advances in understanding of risk factors for incident AF and managing these risk factors. It includes a discussion of lifestyle, somatic, psychological, and socioeconomic risk factors. The available data call for a practice shift towards a more individualised approach considering an increasingly broader range of health and patient factors contributing to AF-related health burden. The review highlights the needs of people living with co-morbidities (especially with multimorbidity), polypharmacy and the role of the changing population demographics affecting the European region and globally.

Item Type:	Article
Uncontrolled Keywords:	Atrial fibrillation, Comorbidities, Lifestyle, Risk factors
Divisions:	Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences Faculty of Health and Life Sciences > Institute of Population Health
Depositing User:	Symplectic Admin
Date Deposited:	06 Mar 2024 10:21
Last Modified:	06 Mar 2024 10:22
DOI:	10.1016/j.lanepe.2023.100784
Open Access URL:	https://doi.org/10.1016/j.lanepe.2023.100784
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3179156