Suputtitada, Areerat, Nopsopon, Tanawin, Rittiphairoj, Thanitsara and Pongpirul, Krit 
ORCID: 0000-0003-3818-9761
(2023)
Intra-Articular Facet Joint Injection of Normal Saline for Chronic Low Back Pain: A Systematic Review and Meta-Analysis.
Medicina (Kaunas, Lithuania), 59 (6).
p. 1038.
Abstract
<i>Objective</i>: This systematic review and meta-analysis compared the patient-reported outcomes of intra-articular facet joint injections of normal saline and selected active substances to identify a more effective agent for treating subacute and chronic low back pain (LBP). <i>Methods</i>: The PubMed, Embase, Scopus, Web of Science, and CENTRAL databases were searched for randomized controlled trials and observational studies published in English. A research quality assessment was performed using ROB2 and ROBINS-I. A meta-analysis was conducted using a random-effects model, and the mean differences (MD) with 95% confidence intervals (CI) in efficacy outcomes, including pain, numbness, disability, and quality of life, were assessed. Results: Of the 2467 potential studies, 3 were included (247 patients). The active substances and normal saline had similar therapeutic effects on pain within 1 h, after 1-1.5 months, and after 3-6 months, with MD and 95% CI of 2.43 and -11.61 to 16.50, -0.63 and -7.97 to 6.72, and 1.90 and -16.03 to 19.83, respectively, as well as on the quality of life after 1 and 6 months. <i>Conclusions</i>: The short- and long-term clinical effects of intra-articular facet joint injections of normal saline are comparable to those of other active substances in patients with LBP.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Zygapophyseal Joint, Humans, Low Back Pain, Injections, Intra-Articular, Quality of Life, Chronic Pain, Saline Solution |
| Divisions: | Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Infection, Veterinary and Ecological Sciences |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 06 Mar 2024 10:48 |
| Last Modified: | 06 Mar 2024 10:49 |
| DOI: | 10.3390/medicina59061038 |
| Open Access URL: | https://doi.org/10.3390/medicina59061038 |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3179178 |
Dimensions
Dimensions
