Biochemical "decoding" of breast ultrasound images with optoacoustic tomography fusion: First-in-human display of lipid and collagen signals on breast ultrasound.


Goh, Yonggeng, Balasundaram, Ghayathri, Tan, Hui Min, Putti, Thomas Choudary, Tang, Siau Wei, Ng, Celene Wei Qi, Buhari, Shaik Ahmad, Fang, Eric, Moothanchery, Mohesh ORCID: 0000-0002-6109-3760, Bi, Renzhe ORCID: 0000-0001-7173-064X et al (show 2 more authors) (2022) Biochemical "decoding" of breast ultrasound images with optoacoustic tomography fusion: First-in-human display of lipid and collagen signals on breast ultrasound. Photoacoustics, 27. 100377-.

Access the full-text of this item by clicking on the Open Access link.

Abstract

To date, studies which utilized ultrasound (US) and optoacoustic tomography (OT) fusion (US-OT) in biochemical differentiation of malignant and benign breast conditions have relied on limited biochemical data such as oxyhaemoglobin (OH) and deoxyhaemoglobin (DH) only. There has been no data of the largest biochemical components of breast fibroglandular tissue: lipid and collagen. Here, the authors believe the ability to image collagen and lipids within the breast tissue could serve as an important milestone in breast US-OT imaging with many potential downstream clinical applications. Hence, we would like to present the first-in-human US-OT demonstration of lipid and collagen differentiation in an excised breast tissue from a 38-year-old female.

Item Type: Article
Uncontrolled Keywords: Breast, Collagen, Lipid, Optoacoustic, Tomography
Divisions: Faculty of Health and Life Sciences
Faculty of Health and Life Sciences > Tech, Infrastructure and Environmental Directorate
Depositing User: Symplectic Admin
Date Deposited: 26 Mar 2024 10:15
Last Modified: 26 Mar 2024 15:35
DOI: 10.1016/j.pacs.2022.100377
Open Access URL: https://doi.org/10.1016/j.pacs.2022.100377
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3179938
Dimensions
Altmetric
CORE (COnnecting REpositories)