Feasibility of abdominal fat quantification on MRI and impact on effectiveness of abdominal compression for radiotherapy motion management.

Daly, M ORCID: 0000-0003-2538-6993, McDaid, L, Nelder, C, Chuter, R, Choudhury, A ORCID: 0000-0002-3561-6580, McWilliam, A, Radhakrishna, G and Eccles, CL ORCID: 0000-0002-5445-5428 (2024) Feasibility of abdominal fat quantification on MRI and impact on effectiveness of abdominal compression for radiotherapy motion management. Technical innovations & patient support in radiation oncology, 29. 100232-.

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Abstract

The impact of fat on abdominal compression effectiveness in abdominal cancers was determined using magnetic resonance imaging (MRI). Visceral and subcutaneous fat were delineated on T2W 3D MRI, and motion change with compression was measured on 2D cine MRI. Results from 16 participants showed no correlation between fat percentage, body mass index (BMI), and motion change. Median BMI was 28.7 (SD, 4.9). Mean motion reduction was 7.8 mm (IQR, 5.0; p = 0.001) with compression. While no direct link was found between fat, BMI, and compression effectiveness, abdominal compression remains crucial for motion management in radiotherapy planning, providing dosimetric benefits.

Item Type:	Article
Uncontrolled Keywords:	Biomedical Imaging, Clinical Research, Obesity, Cancer
Divisions:	Faculty of Health and Life Sciences Faculty of Health and Life Sciences > Institute of Population Health Faculty of Health and Life Sciences > Institute of Population Health > School of Health Sciences
Depositing User:	Symplectic Admin
Date Deposited:	26 Mar 2024 10:34
Last Modified:	26 Apr 2024 11:20
DOI:	10.1016/j.tipsro.2023.100232
Open Access URL:	https://doi.org/10.1016/j.tipsro.2023.100232
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3179954