A pilot study of scanning acoustic microscopy as a tool for measuring arterial stiffness in aortic biopsies



Akhtar, Riaz ORCID: 0000-0002-7963-6874, Cruickshank, J Kennedy, Zhao, Xuegen, Derby, Brian and Weber, Thomas
(2016) A pilot study of scanning acoustic microscopy as a tool for measuring arterial stiffness in aortic biopsies. ARTERY RESEARCH, 13 (C). pp. 1-5.

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Abstract

This study explores the use of scanning acoustic microscopy (SAM) as a potential tool for characterisation of arterial stiffness using aortic biopsies. SAM data is presented for human tissue collected during aortic bypass graft surgery for multi-vessel coronary artery disease. Acoustic wave speed as determined by SAM was compared to clinical data for the patients namely, pulse wave velocity (PWV), blood pressure, cholesterol and glucose levels. There was no obvious trend relating acoustic wave speed to PWV values, and an inverse relationship was found between systolic and diastolic blood pressure and acoustic wave speed. However, in patients with a higher cholesterol or glucose level, the acoustic wave speed increased. A more detailed investigation is needed to relate SAM data to clinical measurements.

Item Type: Article
Uncontrolled Keywords: Arterial stiffening, Scanning acoustic microscopy, Cholesterol, Glucose, Blood pressure, Pulse wave velocity, Acoustic wave speed
Subjects: ?? Q1 ??
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Depositing User: Symplectic Admin
Date Deposited: 16 Dec 2015 11:29
Last Modified: 16 Dec 2022 02:30
DOI: 10.1016/j.artres.2015.11.001
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/2043102