Use of N-Acetylcysteine in Psychiatric Conditions among Children and Adolescents: A Scoping Review.



Naveed, Sadiq, Amray, Afshan, Waqas, Ahmed ORCID: 0000-0002-3772-194X, Chaudhary, Amna M and Azeem, Muhammad W
(2017) Use of N-Acetylcysteine in Psychiatric Conditions among Children and Adolescents: A Scoping Review. Cureus, 9 (11). e1888-e1888.

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Abstract

N-acetylcysteine (NAC) is a well-known antidote for acetaminophen toxicity and is easily available over the counter. It has antioxidant and anti-inflammatory properties and an established tolerance and safety profile. Owing to its neuroprotective effects, its clinical use has recently expanded to include the treatment of different psychiatric and non-psychiatric disorders. Although a number of randomized controlled trials have documented the clinical evidence for NAC, there are no reviews that summarize the evidence. The present scoping review summarizes the study designs, the patient characteristics, the evidence and the limitations in randomized controlled trials designed to explore the efficacy of NAC for psychiatric conditions in the pediatric population.

Item Type: Article
Uncontrolled Keywords: n-actylecysteine, pediatric, children, review, autism, addiction, tourette syndrome, trichotillomania, cannabis, pathological onychophagia
Depositing User: Symplectic Admin
Date Deposited: 04 Apr 2019 15:43
Last Modified: 26 Feb 2024 14:43
DOI: 10.7759/cureus.1888
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3035833