Preparation, structural characterisation and antibacterial properties of Ga-doped sol-gel phosphate-based glass



Pickup, DM, Valappil, SP ORCID: 0000-0001-9646-8406, Moss, RM, Twyman, HL, Guerry, P, Smith, ME, Wilson, M, Knowles, JC and Newport, RJ
(2009) Preparation, structural characterisation and antibacterial properties of Ga-doped sol-gel phosphate-based glass. JOURNAL OF MATERIALS SCIENCE, 44 (7). pp. 1858-1867.

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Abstract

A sol-gel preparation of Ga-doped phosphate-based glass with potential application in antimicrobial devices has been developed. Samples of composition (CaO)0.30(Na2O)0.20-x (Ga2O 3) x (P2O5)0.50 where x = 0 and 0.03 were prepared, and the structure and properties of the gallium-doped sample compared with those of the sample containing no gallium. Analysis of the 31P MAS NMR data demonstrated that addition of gallium to the sol-gel reaction increases the connectivity of the phosphate network at the expense of hydroxyl groups. This premise is supported by the results of the elemental analysis, which showed that the gallium-free sample contains significantly more hydrogen and by FTIR spectroscopy, which revealed a higher concentration of -OH groups in that sample. Ga K-edge extended X-ray absorption fine structure and X-ray absorption near-edge structure data revealed that the gallium ions are coordinated by six oxygen atoms. In agreement with the X-ray absorption data, the high-energy XRD results also suggest that the Ga 3+ ions are octahedrally coordinated with respect to oxygen. Antimicrobial studies demonstrated that the sample containing Ga3+ ions had significant activity against Staphylococcus aureus compared to the control. © 2009 Springer Science+Business Media, LLC.

Item Type: Article
Additional Information: MATCHED FROM WOS ## TULIP Type: Articles/Papers (Journal) ##
Uncontrolled Keywords: hydroxyl groups, gallium-free, spectroscopy, Ga3+ ions, Antimicrobial, Staphylococcus, aureus
Subjects: ?? RK ??
Divisions: Faculty of Health and Life Sciences > Institute of Life Courses and Medical Sciences > School of Dentistry
Depositing User: Symplectic Admin
Date Deposited: 06 Apr 2009 08:56
Last Modified: 15 Dec 2022 07:29
DOI: 10.1007/s10853-008-3237-2
Publisher's Statement : © Springer Science+Business Media, LLC 2009. http://dx.doi.org/10.1007/s10853-008-3237-2. The original publication is available at springerlink.com
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/1062