The extent of degeneration of cruciate ligament is associated with chondrogenic differentiation in patients with osteoarthritis of the knee.



Kumagai, K, Sakai, K, Kusayama, Y, Akamatsu, Y, Sakamaki, K, Morita, S, Sasaki, T, Saito, T and Sakai, Takao ORCID: 0000-0002-7375-5450
(2012) The extent of degeneration of cruciate ligament is associated with chondrogenic differentiation in patients with osteoarthritis of the knee. Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, 20 (11). 1258 - 1267.

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Abstract

This study indicates that chondrogenic differentiation is associated with the progression of degeneration in human ligaments. Our results suggest that the expression of SOX9 as a chondrogenic marker could be an indicator for the extent of degeneration in human ligaments. It remains to be elucidated whether suppression of chondrogenic differentiation can prevent progression of the degenerative process of cruciate ligaments in patients with OA.

Item Type: Article
Depositing User: Symplectic Admin
Date Deposited: 19 Mar 2015 10:13
Last Modified: 12 Nov 2019 14:13
URI: http://livrepository.liverpool.ac.uk/id/eprint/2008461
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