Sperm competition risk drives plasticity in seminal fluid composition

Ramm, Steven, Edward, Dominic, Claydon, Amy, Hammond, Dean ORCID: 0000-0002-6326-8739, Brownridge, Philip, Hurst, Jane ORCID: 0000-0002-3728-9624, Beynon, Rob ORCID: 0000-0003-0857-495X and Stockley, Paula
(2015) Sperm competition risk drives plasticity in seminal fluid composition. BMC Biology, 13 (1). 87-.

This is the latest version of this item.

[img] Text
s12915-015-0197-2.pdf - Unspecified

Download (1MB)


Background Ejaculates contain a diverse mixture of sperm and seminal fluid proteins, the combination of which is crucial to male reproductive success under competitive conditions. Males should therefore tailor the production of different ejaculate components according to their social environment, with particular sensitivity to cues of sperm competition risk (i.e. how likely it is that females will mate promiscuously). Here we test this hypothesis using an established vertebrate model system, the house mouse (Mus musculus domesticus), combining experimental data with a quantitative proteomics analysis of seminal fluid composition. Our study tests for the first time how both sperm and seminal fluid components of the ejaculate are tailored to the social environment. Results Our quantitative proteomics analysis reveals that the relative production of different proteins found in seminal fluid – i.e. seminal fluid proteome composition – differs significantly according to cues of sperm competition risk. Using a conservative analytical approach to identify differential expression of individual seminal fluid components, at least seven of 31 secreted seminal fluid proteins examined showed consistent differences in relative abundance under high versus low sperm competition conditions. Notably three important proteins with potential roles in sperm competition – SVS 6, SVS 5 and CEACAM 10 – were more abundant in the high competition treatment groups. Total investment in both sperm and seminal fluid production also increased with cues of heightened sperm competition risk in the social environment. By contrast, relative investment in different ejaculate components was unaffected by cues of mating opportunities. Conclusions Our study reveals significant plasticity in different ejaculate components, with the production of both sperm and non-sperm fractions of the ejaculate strongly influenced by the social environment. Sperm competition risk is thus shown to be a key factor in male ejaculate production decisions, including driving plasticity in seminal fluid composition.

Item Type: Article
Additional Information: ## TULIP Type: Articles/Papers (Journal) ##
Uncontrolled Keywords: evolution, phenotypic plasticity, proteomics, Random Forest analysis, seminal fluid, sperm competition
Subjects: ?? QH301 ??
?? QH426 ??
?? QL ??
Depositing User: Symplectic Admin
Date Deposited: 05 Nov 2015 11:43
Last Modified: 16 Dec 2022 12:06
DOI: 10.1186/s12915-015-0197-2
Related URLs:
URI: https://livrepository.liverpool.ac.uk/id/eprint/2035379

Available Versions of this Item

  • Sperm competition risk drives plasticity in seminal fluid composition. (deposited 05 Nov 2015 11:43) [Currently Displayed]