Arcolino, Fanny Oliveira, Piella, Agnes Tort, Papadimitriou, Elli, Bussolati, Benedetta, Antonie, Daniel J, Murray, Patricia ORCID: 0000-0003-1316-148X, van den Heuvel, Lamberthus and Levtchenko, Elena
(2015)
Human Urine as a Noninvasive Source of Kidney Cells.
STEM CELLS INTERNATIONAL, 2015.
362562-.
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Abstract
Urine represents an unlimited source of patient-specific kidney cells that can be harvested noninvasively. Urine derived podocytes and proximal tubule cells have been used to study disease mechanisms and to screen for novel drug therapies in a variety of human kidney disorders. The urinary kidney stem/progenitor cells and extracellular vesicles, instead, might be promising for therapeutic treatments of kidney injury. The greatest advantages of urine as a source of viable cells are the easy collection and less complicated ethical issues. However, extensive characterization and in vivo studies still have to be performed before the clinical use of urine-derived kidney progenitors.
Item Type: | Article |
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Additional Information: | Fanny, O. A., Agnès, T. P., Papadimitriou, E., Bussolati, B., Antonie, D. J., Murray, P., . . . Levtchenko, E. (2015). Human urine as a noninvasive source of kidney cells. Stem Cells International, doi:http://dx.doi.org/10.1155/2015/362562 alt_title: none |
Uncontrolled Keywords: | Regenerative Medicine, Clinical Research, Stem Cell Research, Kidney Disease, 2 Aetiology, 2.1 Biological and endogenous factors, Renal and urogenital |
Subjects: | ?? Q1 ?? ?? QP ?? ?? R1 ?? ?? RZ ?? |
Depositing User: | Symplectic Admin |
Date Deposited: | 13 Jan 2016 16:08 |
Last Modified: | 15 Mar 2024 01:11 |
DOI: | 10.1155/2015/362562 |
Publisher's Statement : | Copyright © 2015 Fanny Oliveira Arcolino et al.This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited |
Related URLs: | |
URI: | https://livrepository.liverpool.ac.uk/id/eprint/2046541 |