Transmission dynamics of a zoonotic pathogen within and between wildlife host species

Begon, M ORCID: 0000-0003-1715-5327, Hazel, SM, Baxby, D, Bown, K, Cavanagh, R, Chantrey, J ORCID: 0000-0002-4801-7034, Jones, T and Bennett, M (1999) Transmission dynamics of a zoonotic pathogen within and between wildlife host species PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 266 (1432). pp. 1939-1945. ISSN 0962-8452, 1471-2954

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Abstract

The transmission dynamics of the cowpox virus infection have been quantified in two mixed populations of bank voles (Clethrionmys glareolus) and wood mice (Apodemus sylvaticus), through analyses of detailed time-series of the numbers of susceptible, infectious and newly infected individuals. The cowpox virus is a zoonosis which circulates in these rodent hosts and has been shown to have an adverse effect on reproductive output. The transmission dynamics within species is best described as frequency dependent rather than density dependent, contrary to the 'mass action' assumption of most previous studies, both theoretical and empirical. Estimation of a transmission coefficient for each species in each population also allows annual and seasonal variations in transmission dynamics to be investigated through an analysis of regression residuals. Transmission between host species is found to be negligible despite their close cohabitation. The consequences of this for the combining ability of hosts as zoonotic reservoirs, and for apparent competition between hosts, are discussed.

Item Type:	Article
Additional Information:	## TULIP Type: Articles/Papers (Journal) ## official_url: <Go to ISI>://000083173100002
Uncontrolled Keywords:	cowpox, Apodemus, Clethrionomys, transmission dynamics, host-pathogen dynamics, apparent competition
Depositing User:	Symplectic Admin
Date Deposited:	11 Apr 2016 10:11
Last Modified:	16 Jun 2026 07:46
DOI:	10.1098/rspb.1999.0870
Related Websites:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3000139
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