Understanding the physiological roles of the neuronal calcium sensor proteins

Burgoyne, Robert D ORCID: 0000-0002-9219-0387 and Haynes, Lee P (2012) Understanding the physiological roles of the neuronal calcium sensor proteins MOLECULAR BRAIN, 5 (1). 2-. ISSN 1756-6606, 1756-6606

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Abstract

Calcium signalling plays a crucial role in the control of neuronal function and plasticity. Changes in neuronal Ca²⁺ concentration are detected by Ca²⁺-binding proteins that can interact with and regulate target proteins to modify their function. Members of the neuronal calcium sensor (NCS) protein family have multiple non-redundant roles in the nervous system. Here we review recent advances in the understanding of the physiological roles of the NCS proteins and the molecular basis for their specificity. © 2012 Burgoyne and Haynes; licensee BioMed Central Ltd.

Item Type:	Article
Additional Information:	Journal article Molecular brain Mol Brain. 2012 Jan 23;5(1):2. ## TULIP Type: Articles/Papers (Journal) ##
Uncontrolled Keywords:	Calcium, Calcium-sensor, EF-hand, neuronal signalling, protein complex, protein structure
Depositing User:	Symplectic Admin
Date Deposited:	28 Apr 2016 10:18
Last Modified:	16 Jun 2026 05:35
DOI:	10.1186/1756-6606-5-2
Open Access URL:	http://molecularbrain.biomedcentral.com/articles/1...
Related Websites:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3000899
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