microRNA: emerging biomarkers in human disease and profiling challenges

Zhang, J Eunice ORCID: 0000-0003-1813-2207 (2016) microRNA: emerging biomarkers in human disease and profiling challenges. [Website Content]

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Abstract

<jats:p>Over the last decade, a rapid growth in the field of micro(mi)RNA research has been evident. Profiles of miRNAs have been shown to reflect pathological conditions and have been implicated as potential biomarkers in the diagnosis and evaluation of human diseases. In this article, an overview of miRNA discovery and biogenesis is provided. Recent advances in using circulating miRNA as biomarkers in human diseases are discussed, along with the challenges researchers are facing in miRNA profiling and future diagnostic prospects.</jats:p>

Item Type:	Website Content
Uncontrolled Keywords:	31 Biological Sciences, 3102 Bioinformatics and Computational Biology, Genetics, Biotechnology, 4.2 Evaluation of markers and technologies, 4.1 Discovery and preclinical testing of markers and technologies, 3 Good Health and Well Being
Depositing User:	Symplectic Admin
Date Deposited:	26 May 2016 10:02
Last Modified:	26 Sep 2025 18:37
DOI:	10.1042/bio03802026
Related Websites:	Author URL
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3001202