Lawman, S 
ORCID: 0000-0003-2695-4366, Dong, Y, Williams, BM ORCID: 0000-0001-5930-287X, Romano, V ORCID: 0000-0002-5148-7643, Kaye, S ORCID: 0000-0003-0390-0592, Harding, SP ORCID: 0000-0003-4676-1158, Willoughby, C, Shen, YC ORCID: 0000-0002-8915-1993 and Zheng, Y ORCID: 0000-0002-7873-0922
(2016)
High Resolution Corneal and Single Pulse Imaging with Line Field Spectral Domain Optical Coherence Tomography.
Optics Express, 24 (11).
pp. 12395-12405.
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Abstract
We report the development of a Spectral Domain Line Field Optical Coherence Tomography (LF-OCT) system, using a broad bandwidth and spatial coherent Super-Continuum (SC) source. With conventional quasi-Continuous Wave (CW) setup we achieve axial resolutions up to 2.1 μm in air and 3D volume imaging speeds up to 213 kA-Scan/s. Furthermore, we report the use of a single SC pulse, of 2 ns duration, to temporally gate an OCT B-Scan image of 70 A-Scans. This is the equivalent of 35 GA-Scans/s. We apply the CW setup for high resolution imaging of the fine structures of a human cornea sample ex-vivo. The single pulse setup is applied to imaging of a coated pharmaceutical tablet. The fixed pattern noise due to spectral noise is removed by subtracting the median magnitude A-Scan. We also demonstrate that the Fourier phase can be used to remove aberration caused artefacts.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Biomedical Imaging, Bioengineering, Clinical Research |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 02 Jun 2016 10:01 |
| Last Modified: | 15 Mar 2024 14:48 |
| DOI: | 10.1364/OE.24.012395 |
| Related URLs: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3001477 |
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