Stable, polymer-directed and SPION-nucleated magnetic amphiphilic block copolymer nanoprecipitates with readily reversible assembly in magnetic fields

Giardiello, Marco ORCID: 0000-0003-0560-4711, Hatton, Fiona L, Slater, Rebecca A, Chambon, Pierre, North, Jocelyn, Peacock, Anita K, He, Tao, McDonald, Tom O ORCID: 0000-0002-9273-9173, Owen, Andrew ORCID: 0000-0002-9819-7651 and Rannard, Steve P ORCID: 0000-0002-6946-1097 (2016) Stable, polymer-directed and SPION-nucleated magnetic amphiphilic block copolymer nanoprecipitates with readily reversible assembly in magnetic fields. Nanoscale, 8 (13). pp. 7224-7231. ISSN 2040-3364, 2040-3372

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Abstract

The formation of inorganic–organic magnetic nanocomposites using reactive chemistry often leads to a loss of super-paramagnetisim when conducted in the presence of iron oxide nanoparticles. We present here a low energy and chemically-mild process of co-nanoprecipitation using SPIONs and homopolymers or amphiphilic block copolymers, of varying architecture and hydrophilic/hydrophobic balance, which efficiently generates near monodisperse SPION-containing polymer nanoparticles with complete retention of magnetism, and highly reversible aggregation and redispersion behaviour. When linear and branched block copolymers with inherent water-solubility are used, a SPION-directed nanoprecipitation mechanism appears to dominate the nanoparticle formation presenting new opportunities for tailoring and scaling highly functional systems for a range of applications.

Item Type:	Article
Uncontrolled Keywords:	3403 Macromolecular and Materials Chemistry, 40 Engineering, 34 Chemical Sciences, Nanotechnology, Bioengineering
Depositing User:	Symplectic Admin
Date Deposited:	22 Aug 2016 07:50
Last Modified:	05 Jun 2025 18:17
DOI:	10.1039/c6nr00788k
Related Websites:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3003000