Management of obesity

Bray, George A, Fruhbeck, Gema, Ryan, Donna H and Wilding, John PH ORCID: 0000-0003-2839-8404 (2016) Management of obesity. LANCET, 387 (10031). pp. 1947-1956.

Text Bray_Lancet 2015.10.12 R5 THELANCET-D-15-01286R5.pdf - Author Accepted Manuscript Download (2MB)

Abstract

A modern approach to obesity acknowledges the multifactorial determinants of weight gain and the health benefits to be derived from weight loss. Foundational to any weight loss effort is lifestyle change, diet, and increased physical activity. The approach should be a high quality diet to which patients will adhere accompanied by an exercise prescription describing frequency, intensity, type, and time with a minimum of 150 min moderate weekly activity. For patients who struggle with weight loss and who would receive health benefit from weight loss, management of medications that are contributing to weight gain and use of approved medications for chronic weight management along with lifestyle changes are appropriate. Medications approved in the USA or European Union are orlistat, naltrexone/bupropion, and liraglutide; in the USA, lorcaserin and phentermine/topiramate are also available. Surgical management (gastric banding, sleeve gastrectomy, and Roux-en Y gastric bypass) can produce remarkable health improvement and reduce mortality for patients with severe obesity.

Item Type:	Article
Uncontrolled Keywords:	Humans, Obesity, Weight Loss, Anti-Obesity Agents, Treatment Outcome, Exercise Therapy, Diet, Reducing, Risk Reduction Behavior, Bariatric Surgery
Depositing User:	Symplectic Admin
Date Deposited:	26 Oct 2016 11:44
Last Modified:	19 Jan 2023 07:27
DOI:	10.1016/S0140-6736(16)00271-3
Related URLs:	Author Publisher
URI:	https://livrepository.liverpool.ac.uk/id/eprint/3004049