The recent invasion of natural Drosophila simulans populations by the P-element

Kofler, Robert, Hill, Tom, Nolte, Viola, Betancourt, Andrea J ORCID: 0000-0001-9351-1413 and Schlötterer, Christian
(2015) The recent invasion of natural Drosophila simulans populations by the P-element. Proceedings of the National Academy of Sciences, 112 (21). 6659 - 6663.

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The P-element is one of the best understood eukaryotic transposable elements. It invaded Drosophila melanogaster populations within a few decades but was thought to be absent from close relatives, including Drosophila simulans. Five decades after the spread in D. melanogaster, we provide evidence that the P-element has also invaded D. simulans. P-elements in D. simulans appear to have been acquired recently from D. melanogaster probably via a single horizontal transfer event. Expression data indicate that the P-element is processed in the germ line of D. simulans, and genomic data show an enrichment of P-element insertions in putative origins of replication, similar to that seen in D. melanogaster. This ongoing spread of the P-element in natural populations provides a unique opportunity to understand the dynamics of transposable element spread and the associated piwi-interacting RNAs defense mechanisms.

Item Type: Article
Uncontrolled Keywords: P-element, transposable elements, Drosophila simulans, population genomics, Pool-seq
Depositing User: Symplectic Admin
Date Deposited: 31 Oct 2016 09:45
Last Modified: 27 May 2020 10:12
DOI: 10.1073/pnas.1500758112
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