Kofler, Robert, Hill, Tom, Nolte, Viola, Betancourt, Andrea J 
ORCID: 0000-0001-9351-1413 and Schlötterer, Christian
(2015)
The recent invasion of natural Drosophila simulans populations by the P-element
Proceedings of the National Academy of Sciences, 112 (21).
pp. 6659-6663.
ISSN 0027-8424, 1091-6490
Abstract
The P-element is one of the best understood eukaryotic transposable elements. It invaded Drosophila melanogaster populations within a few decades but was thought to be absent from close relatives, including Drosophila simulans. Five decades after the spread in D. melanogaster, we provide evidence that the P-element has also invaded D. simulans. P-elements in D. simulans appear to have been acquired recently from D. melanogaster probably via a single horizontal transfer event. Expression data indicate that the P-element is processed in the germ line of D. simulans, and genomic data show an enrichment of P-element insertions in putative origins of replication, similar to that seen in D. melanogaster. This ongoing spread of the P-element in natural populations provides a unique opportunity to understand the dynamics of transposable element spread and the associated piwi-interacting RNAs defense mechanisms.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | P-element, transposable elements, Drosophila simulans, population genomics, Pool-seq |
| Depositing User: | Symplectic Admin |
| Date Deposited: | 31 Oct 2016 09:45 |
| Last Modified: | 01 Mar 2026 01:45 |
| DOI: | 10.1073/pnas.1500758112 |
| Open Access URL: | http://www.pnas.org/content/112/21/6659.full |
| Related Websites: | |
| URI: | https://livrepository.liverpool.ac.uk/id/eprint/3004201 |
| Disclaimer: | The University of Liverpool is not responsible for content contained on other websites from links within repository metadata. Please contact us if you notice anything that appears incorrect or inappropriate. |
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