Temperature sensitivity of red blood cell physiology in Atlantic cod, Gadus morhua : comparative, molecular, evolutionary and environmental aspects


Barlow, SL (2016) Temperature sensitivity of red blood cell physiology in Atlantic cod, Gadus morhua : comparative, molecular, evolutionary and environmental aspects PhD thesis, University of Liverpool.

[thumbnail of 200502185_Mar2016.pdf] Text
200502185_Mar2016.pdf - Unspecified
Download (2MB)

Abstract

The ability of fish to withstand increased temperatures has been directly linked with the capacity of their oxygen transport system and its ability to supply the tissues of the body with sufficient oxygen to meet demand. Therefore studies on the effects of temperature on the oxygen transport systems of aquatic organisms are important for understanding their capacity to cope with climate change. An early study in Atlantic cod (Gadus morhua) suggested haemoglobin I genotype affects temperature sensitivity of red blood cell oxygen binding, with one genotype found to be temperature insensitive. However this research had many limitations and subsequent research remains inconclusive as to the significance of the haemoglobin I polymorphism. In the most comprehensive study to date, results showed statistically indistinguishable red blood cell O2 binding between any of the three haemoglobin I genotypes in wild-caught Atlantic cod. Red blood cells had an unusually low O2 affinity, with reduced or even reversed thermal sensitivity, suggesting an endothermic nature to oxygen binding rarely seen in ectothermic teleosts. Reduced thermal sensitivity of oxygen binding is often attributed to the presence of increased pH sensitivity ... (continues)

Item Type: Thesis (PhD)
Divisions: Faculty of Health & Life Sciences
Depositing User: Symplectic Admin
Date Deposited: 13 Dec 2016 09:46
Last Modified: 09 Aug 2025 20:21
DOI: 10.17638/03004526
Supervisors:
URI: https://livrepository.liverpool.ac.uk/id/eprint/3004526
Disclaimer: The University of Liverpool is not responsible for content contained on other websites from links within repository metadata. Please contact us if you notice anything that appears incorrect or inappropriate.
Altmetric
CORE (COnnecting REpositories)